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Molecular Genetics

Molecular Genetics

Personnel

We are interested in the molecular control of myogenesis. Skeletal muscle is the largest tissue in human body. Its formation requires the activation and expansion of muscle stem cells, and subsequent differentiation, fusion and maturation of their progenies. Understanding the mechanisms that drive these cellular events is not only essential to…

Mammalian developmental genetics: mechanisms that control tissue patterns during mammalian embryonic development; signaling pathways that function in cell fate specification; identification of novel regulators of Hedgehog signaling pathways in central nervous system

Transcriptional and epigenetic mechanisms regulating preimplantation development, pluripotency, differentiation and cellular reprogramming in humans

Systems biology of host-pathogen interactions, Nuclear and organellar genome evolution in eukaryotic parasites, Databases, Ontologies, Data mining and Data integration of 'omics (genome, transcriptome, proteome, metabolome, lipidome), clinical, immunological, epidemiological and experimental metadata.  

Molecular evolutionary genetics of gene families and phytoremediation: molecular genetics and evolution of plant gen expression; environmental molecular biology; actin and actin-binding proteins encoded by gene families in plants; subfamilies of encoded protein isovariants co-evolved specific interactions in tissues and organs of Arabidopsis;…

Non-coding RNA function, cancer, and genome defense: biogenesis, trafficking, and function of non-coding RNA-protein complexes; goal to improve understanding and treatment of human disease

My research interest lies in Nutritional Genomics, a new interdisciplinary field bridging Nutritional Sciences and Human Genomics. I am interested in identifying genetic variants that historically helped human populations adapted to local diets and currently underlie individual differences in nutrient metabolism and metabolic disease risks. In…

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