Meagher Laboratory

 

The actin-based proteome is encoded by at least 250 genes
Gene/Category
Number of genes
Gene/Category
Number of genes
Actins
10
F-actin crosslinking/bundling
65-170
ARPs
8
F-actin severaing
10-20
Actin monomer binding
17
Misc-actin binding
50
F-actin capping
2
Myosin-motor protein
20
Number total genes
180-295
 
The evolutionary origin of the actin-based proteome in plants is perhaps best revealed by analyzing relevant cytoskeletal gene families: In Arabidopsis 200 of these genes are in the 16 families listed below.
  Actins √
ARPs √
Profilins √
ADFs
Myosins
eIF1as
Filamins
Fimbrins		 Ezrins
Sla2p
Gelsolins/Villins
Espins
Tropomyosins
Troponin C
Anillins
Annexins