| 1. Profilin promotes actin assembly on the barbed ends of growing F-actin filaments | 4. Profilin plays a role in ADP to ATP exchange in actin monomers preparing actin for polymerization into F-actin |
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| 2. Profilin sequesters G-actin monomers in heterodimeric profilactin complexes |
5. Profilin binds several other ligands such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the ARP2/3 complex |
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| 3. Profilin promotes depolymerization of actin filaments by binding G-actin | ||
| Kandasamy et al., 2002; Huang et al., 1996 |