Meagher Laboratory E.C. McKinney CV

PUBLICATIONS

36. Deal, R.B., Topp, C.N., McKinney, E.C., and Meagher, R.B. (2007) Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z. Plant Cell 19, 74-83.

35. Meagher, R.B., Kandasamy, M.K., Deal, R.B., and McKinney, E.C. (2007) Actin-related proteins in chromatin-level control of the cell cycle and developmental transitions. Trends Cell Biol 17, 325-32.

34. Kandasamy, M.K., Burgos-Rivera, B., McKinney, E.C., Ruzicka, D., and Meagher, R.B. (2007) Class-specific interactions of profilin and ADF isovariants with actin in the regulation of plant development. Plant Cell. In Press.

33. Ruzicka, D., Kandasamy, M.K., McKinney, E.C., Bursos-Rivera, B., and Meagher, R.B. (2007) The ancient subclasses of Arabidopsis ACTIN DEPOLYMERIZING FACTOR genes exhibit novel and differential expression. Plant J. In Press.

32. Dhankher, O.P., Rosen, B.P., McKinney, E.C., and Meagher, R.B. (2006) Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2). Proc Natl Acad Sci U S A 103, 5413-5418.

31. Deal, R.B., Kandasamy, M.K., McKinney, E.C. and Meagher, R.B. 2005. The Nuclear Actin-Related Protein ARP6 Is a Pleiotropic Developmental Regulator Required for the Maintenance of FLOWERING LOCUS C Expression and Repression of Flowering in Arabidopsis. Plant Cell 17: 2633-2646.

30. Kandasamy, M.K., Deal, R.B., McKinney, E.C. and Meagher, R.B. 2005a. Silencing the nuclear actin-related protein AtARP4 in Arabidopsis has multiple effects on plant development, including early flowering and delayed floral senescence. Plant J 41: 845-58.

29. Kandasamy, M.K., McKinney, E.C., Deal, R.B. and Meagher, R.B. 2005b. ARP7 is an essential actin-related protein required for embryo development and its knockdown affects plant architecture and flower senescence in Arabidopsis. Plant Physiol 138: 2019-2032.

28. Kim, T., Balish, R.S., Heaton, A.C.P., McKinney, E.C. and Meagher, R.B. 2005. Engineering a Root-Specific, Repressor-Operator Gene Complex. Plant Biotech 3: 571-582.

27. Meagher, R.B., Deal, R.B., Kandasamy, M.K. and McKinney, E.C. 2005b. Nuclear actin-related proteins as epigenetic regulators of development. Plant Physiol 139: 1576-85.

26. Pawloski, L.C., Deal, R.B., McKinney, E.C., Burgos-Rivera, B. and Meagher, R.B. 2005. Inverted repeat PCR for the rapid assembly of constructs to induce RNA interference. Plant Cell Physiol 46: 1872-8.

25. Kandasamy, M.K., Deal, R.B., McKinney, E.C. and Meagher, R.B. 2004. Plant actin-related proteins. Trends Plant Sci 9: 196-202.

24. Kandasamy, M.K., McKinney, E.C., and Meagher, R.B. 2003. Cell cycle dependent association of Arabidopsis actin-related proteins AtARP4 and AtARP7 with the nucleus. Plant Journal 33:939-948.

23. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (2002a). Functional non-equivalency of actin isovariants in Arabidopsis. Mol Biol Cell 13, 251-261.

22. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (2002b). Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. Cell Motil Cytoskeleton 52, 22-32.

21. McKinney, E. C., Kandasamy, M. K., and Meagher, R. B. (2002). Arabidopsis contains ancient classes of differentially expressed actin- related protein genes. Plant Physiol 128, 997-1007.

20. Kandasamy, M. K., Gilliland, L. U., McKinney, E. C., and Meagher, R. B. (2001). One plant actin isovariant, ACT7, is induced by auxin and required for normal callus formation. Plant Cell 13, 1541-1554.

19. McKinney, E. C., Kandasamy, M. K., and Meagher, R. B. (2001). Small changes in the regulation of one Arabidopsis profilin isovariant, prf1, alter seedling development. Plant Cell 13, 1179-1191.

18. Meagher, R. B., McKinney, E. C., and Kandasamy, M. K. (2000a). The significance of diversity in the plant actin gene family: Studies in Arabidopsis. In Actin: A dynamic framework for multiple plant cell functions, C. J. Staiger, F. Baluska, D. Volkmann, and P. Barlow, eds. (Dordrecht, The Netherlands, Klewer Academic Publishers), pp. 3-27.

17. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (1999). The late pollen-specific actins in angiosperms. Plant J 18, 681-691.

16. Meagher, R. B., McKinney, E. C., and Vitale, A. V. (1999a). The evolution of new structures: clues from plant cytoskeletal genes. Trends Genet 15, 278-284.

15. Meagher, R. B., McKinney, E. C., and Kandasamy, M. K. (1999b). Isovariant dynamics expand and buffer the responses of complex systems: the diverse plant actin gene family. Plant Cell 11, 995-1006.

14. Gilliland, L. U., McKinney, E. C., Asmussen, M. A., and Meagher, R. B. (1998). Detection of deleterious genotypes in multigenerational studies. I. Disruptions in individual Arabidopsis actin genes. Genetics 149, 717-725.

13. McKinney, E., and Meagher, R. (1998). Members of the Arabidopsis actin gene family are widely dispersed in the genome. Genetics 149, 663-675.

12. Huang, S., An, Y.-Q., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1997). The Arabidopsis ACT11 actin gene is strongly expressed in tissues of the emerging inflorescence, pollen and developing ovules. Plant Mol Biol 33, 125-139.

11. An, Y.-Q., Huang, S., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996a). Conserved expression of the Arabidopsis ACT1 and ACT3 actin subclass in organ primordia and mature pollen. Plant Cell 8, 15-30.

10. An, Y.-Q., McDowell, J. M., Huang, S., McKinney, E. C., Chambliss, S., and Meagher, R. B. (1996b). Strong, constitutive expression of the Arabidopsis ACT2/ACT8 actin subclass in vegetative tissues. Plant J 10, 107-121.

9. Huang, S., An, Y.-Q., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996a). The Arabidopsis ACT4/ACT12 actin gene subclass is strongly expressed in post-mitotic pollen. Plant J 10, 189-202.

8. McDowell, J. M., An, Y.-Q., McKinney, E. C., Huang, S., and Meagher, R. B. (1996a). The Arabidopsis ACT7 actin gene is expressed in rapidly developing tissues and responds to several external stimuli. Plant Physiol 111, 699-711.

7. McDowell, J. M., Huang, S., McKinney, E. C., An, Y. Q., and Meagher, R. B. (1996b). Structure and evolution of the actin gene family in Arabidopsis thaliana. Genetics 142, 587-602.

6. Senecoff, J. F., McKinney, E. C., and Meagher, R. B. (1996). DeNovo Purine synthesis in Arabidopsis thaliana II. The Pur 7 gene encoding 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase is expressed in rapidly dividing tissues. Plant Physiol 112, 905-917.

5. Y-Q., A., Huang, S., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996). Conserved expression of the Arabidopsis ACT1 and ACT 3 actin subclass in organ primordia and mature pollen. The Plant Cell 8, 15-30.

4. Valenta, R., Ferreira, F., Grote, M., Swoboda, I., Vrtala, S., Duchene, M., Deviller, P., Meagher, R., McKinney, E., Heberle-Bores, E., et al. (1993). Identification of profilin as an actin binding protein in higher plants. J Biol Chem 268, 22777-22781.

3. McLean, B. G., Huang, S., McKinney, E. C., and Meagher, R. B. (1990). Plants contain highly divergent actin isovariants. Cell Motil Cytoskeleton 17, 276-290.

2. Allen, R.D., Cohen, E.A., Vonder Haar, R.A., Adams, C.A., Ma, D.P., Nessler, C.L., and Thomas., T.L. (1987) Sequence and expression of a gene encoding an albumin stgorage protein in sunflower. Mol. Gen. Genet. 415-424.

1. Allen, R.D., Cohen, E.A., Orth, K.A., Vonder Haar, R.A., Ma, D.P., Nessler, C.L., and Thomas., T.L. (1986) Expression of Embryo Specific Genes in Sunflower. In Molecular Approaches to Developmental Biology, R.A. Firtel and E.H. Davidson, edigtors, Alan R. Liss Inc., New York. pp415-424.

	Elizabeth C. McKinney
	Research Professional III Department of Genetics Life Science Building University of Georgia Athens, GA 30602
	Phone: 706-542-1410 Fax: 706-542-1387 E-mail: emckiney@uga.edu
	EDUCATION 1986 Texas A&M University, College Station Texas- M.S. in Biology 1984 Texas A&M University, College Station Texas- B.S. in Botany
PROFESSIONAL EXPERIENCE 2005 to Present. Research Professional III in the Meagher laboratory examining the evolution, expression, and molecular cell biology of the actin, profilin and actin-related protein gene families in plants. 1999 to 2005. Research Coordinator II in the Meagher laboratory examining the evolution, expression, and molecular cell biology of the actin, profilin and ARP gene families in plants. 1986 to 1999. Research Coordinator I in the Meagher laboratory examining the expression and molecular cell biology of the actin and profilin gene families in plants.
PUBLICATIONS 36. Deal, R.B., Topp, C.N., McKinney, E.C., and Meagher, R.B. (2007) Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z. Plant Cell 19, 74-83. 35. Meagher, R.B., Kandasamy, M.K., Deal, R.B., and McKinney, E.C. (2007) Actin-related proteins in chromatin-level control of the cell cycle and developmental transitions. Trends Cell Biol 17, 325-32. 34. Kandasamy, M.K., Burgos-Rivera, B., McKinney, E.C., Ruzicka, D., and Meagher, R.B. (2007) Class-specific interactions of profilin and ADF isovariants with actin in the regulation of plant development. Plant Cell. In Press. 33. Ruzicka, D., Kandasamy, M.K., McKinney, E.C., Bursos-Rivera, B., and Meagher, R.B. (2007) The ancient subclasses of Arabidopsis ACTIN DEPOLYMERIZING FACTOR genes exhibit novel and differential expression. Plant J. In Press. 32. Dhankher, O.P., Rosen, B.P., McKinney, E.C., and Meagher, R.B. (2006) Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2). Proc Natl Acad Sci U S A 103, 5413-5418. 31. Deal, R.B., Kandasamy, M.K., McKinney, E.C. and Meagher, R.B. 2005. The Nuclear Actin-Related Protein ARP6 Is a Pleiotropic Developmental Regulator Required for the Maintenance of FLOWERING LOCUS C Expression and Repression of Flowering in Arabidopsis. Plant Cell 17: 2633-2646. 30. Kandasamy, M.K., Deal, R.B., McKinney, E.C. and Meagher, R.B. 2005a. Silencing the nuclear actin-related protein AtARP4 in Arabidopsis has multiple effects on plant development, including early flowering and delayed floral senescence. Plant J 41: 845-58. 29. Kandasamy, M.K., McKinney, E.C., Deal, R.B. and Meagher, R.B. 2005b. ARP7 is an essential actin-related protein required for embryo development and its knockdown affects plant architecture and flower senescence in Arabidopsis. Plant Physiol 138: 2019-2032. 28. Kim, T., Balish, R.S., Heaton, A.C.P., McKinney, E.C. and Meagher, R.B. 2005. Engineering a Root-Specific, Repressor-Operator Gene Complex. Plant Biotech 3: 571-582. 27. Meagher, R.B., Deal, R.B., Kandasamy, M.K. and McKinney, E.C. 2005b. Nuclear actin-related proteins as epigenetic regulators of development. Plant Physiol 139: 1576-85. 26. Pawloski, L.C., Deal, R.B., McKinney, E.C., Burgos-Rivera, B. and Meagher, R.B. 2005. Inverted repeat PCR for the rapid assembly of constructs to induce RNA interference. Plant Cell Physiol 46: 1872-8. 25. Kandasamy, M.K., Deal, R.B., McKinney, E.C. and Meagher, R.B. 2004. Plant actin-related proteins. Trends Plant Sci 9: 196-202. 24. Kandasamy, M.K., McKinney, E.C., and Meagher, R.B. 2003. Cell cycle dependent association of Arabidopsis actin-related proteins AtARP4 and AtARP7 with the nucleus. Plant Journal 33:939-948. 23. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (2002a). Functional non-equivalency of actin isovariants in Arabidopsis. Mol Biol Cell 13, 251-261. 22. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (2002b). Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. Cell Motil Cytoskeleton 52, 22-32. 21. McKinney, E. C., Kandasamy, M. K., and Meagher, R. B. (2002). Arabidopsis contains ancient classes of differentially expressed actin- related protein genes. Plant Physiol 128, 997-1007. 20. Kandasamy, M. K., Gilliland, L. U., McKinney, E. C., and Meagher, R. B. (2001). One plant actin isovariant, ACT7, is induced by auxin and required for normal callus formation. Plant Cell 13, 1541-1554. 19. McKinney, E. C., Kandasamy, M. K., and Meagher, R. B. (2001). Small changes in the regulation of one Arabidopsis profilin isovariant, prf1, alter seedling development. Plant Cell 13, 1179-1191. 18. Meagher, R. B., McKinney, E. C., and Kandasamy, M. K. (2000a). The significance of diversity in the plant actin gene family: Studies in Arabidopsis. In Actin: A dynamic framework for multiple plant cell functions, C. J. Staiger, F. Baluska, D. Volkmann, and P. Barlow, eds. (Dordrecht, The Netherlands, Klewer Academic Publishers), pp. 3-27. 17. Kandasamy, M. K., McKinney, E. C., and Meagher, R. B. (1999). The late pollen-specific actins in angiosperms. Plant J 18, 681-691. 16. Meagher, R. B., McKinney, E. C., and Vitale, A. V. (1999a). The evolution of new structures: clues from plant cytoskeletal genes. Trends Genet 15, 278-284. 15. Meagher, R. B., McKinney, E. C., and Kandasamy, M. K. (1999b). Isovariant dynamics expand and buffer the responses of complex systems: the diverse plant actin gene family. Plant Cell 11, 995-1006. 14. Gilliland, L. U., McKinney, E. C., Asmussen, M. A., and Meagher, R. B. (1998). Detection of deleterious genotypes in multigenerational studies. I. Disruptions in individual Arabidopsis actin genes. Genetics 149, 717-725. 13. McKinney, E., and Meagher, R. (1998). Members of the Arabidopsis actin gene family are widely dispersed in the genome. Genetics 149, 663-675. 12. Huang, S., An, Y.-Q., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1997). The Arabidopsis ACT11 actin gene is strongly expressed in tissues of the emerging inflorescence, pollen and developing ovules. Plant Mol Biol 33, 125-139. 11. An, Y.-Q., Huang, S., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996a). Conserved expression of the Arabidopsis ACT1 and ACT3 actin subclass in organ primordia and mature pollen. Plant Cell 8, 15-30. 10. An, Y.-Q., McDowell, J. M., Huang, S., McKinney, E. C., Chambliss, S., and Meagher, R. B. (1996b). Strong, constitutive expression of the Arabidopsis ACT2/ACT8 actin subclass in vegetative tissues. Plant J 10, 107-121. 9. Huang, S., An, Y.-Q., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996a). The Arabidopsis ACT4/ACT12 actin gene subclass is strongly expressed in post-mitotic pollen. Plant J 10, 189-202. 8. McDowell, J. M., An, Y.-Q., McKinney, E. C., Huang, S., and Meagher, R. B. (1996a). The Arabidopsis ACT7 actin gene is expressed in rapidly developing tissues and responds to several external stimuli. Plant Physiol 111, 699-711. 7. McDowell, J. M., Huang, S., McKinney, E. C., An, Y. Q., and Meagher, R. B. (1996b). Structure and evolution of the actin gene family in Arabidopsis thaliana. Genetics 142, 587-602. 6. Senecoff, J. F., McKinney, E. C., and Meagher, R. B. (1996). DeNovo Purine synthesis in Arabidopsis thaliana II. The Pur 7 gene encoding 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase is expressed in rapidly dividing tissues. Plant Physiol 112, 905-917. 5. Y-Q., A., Huang, S., McDowell, J. M., McKinney, E. C., and Meagher, R. B. (1996). Conserved expression of the Arabidopsis ACT1 and ACT 3 actin subclass in organ primordia and mature pollen. The Plant Cell 8, 15-30. 4. Valenta, R., Ferreira, F., Grote, M., Swoboda, I., Vrtala, S., Duchene, M., Deviller, P., Meagher, R., McKinney, E., Heberle-Bores, E., et al. (1993). Identification of profilin as an actin binding protein in higher plants. J Biol Chem 268, 22777-22781. 3. McLean, B. G., Huang, S., McKinney, E. C., and Meagher, R. B. (1990). Plants contain highly divergent actin isovariants. Cell Motil Cytoskeleton 17, 276-290. 2. Allen, R.D., Cohen, E.A., Vonder Haar, R.A., Adams, C.A., Ma, D.P., Nessler, C.L., and Thomas., T.L. (1987) Sequence and expression of a gene encoding an albumin stgorage protein in sunflower. Mol. Gen. Genet. 415-424. 1. Allen, R.D., Cohen, E.A., Orth, K.A., Vonder Haar, R.A., Ma, D.P., Nessler, C.L., and Thomas., T.L. (1986) Expression of Embryo Specific Genes in Sunflower. In Molecular Approaches to Developmental Biology, R.A. Firtel and E.H. Davidson, edigtors, Alan R. Liss Inc., New York. pp415-424.