Andrew Paterson
Distinguished Research Professor
Ph.D. (1988) Cornell University
Phone: 706-583-0162
Email: paterson@uga.edu
See my Laboratory Home Page

Research Interests
Our laboratory is interested in the identification and implementation of DNA diagnostic tools that are predictive of specific plant characteristics such as disease resistance, improved productivity, or improved quality. We work in close collaboration with scientists in several applied agricultural disciplines; thereby contributing to accelerated improvement of plants to better suit human purposes by traditional means such as classical plant breeding. We are also interested in the identification of specific genes that are responsible for characteristics important to plant development, evolution, or agriculture, and elucidating the function(s) of these genes. Finally, we are interested in elucidating plant biodiversity at the genic and genomic level; gaining better understanding of the 200-million year history of flowering plant diversification from a hypothetical common ancestor, and better understanding specific molecular-level events that have contributed to the ability of flowering plants to colonize much of the Earth.
  • Wang, J., P.H. Moore, A.H. Paterson and R. Ming. 2007. Sex Chromosomes in Flowering Plants. American Journal of Botany 94: 141-150.
  • Grover, C.E., H.R. Kim, R.A. Wing, A.H. Paterson and J.F. Wendel. 2007. Microcolinearity and genome evolution in the AdhA region of diploid and polyploid cotton (Gossypium). Plant Journal 50: 995-1006.
  • Lohithaswa, H.C., F.A. Feltus, H.P. Singh, C.D. Bacon, C. D. Bailey and A.H. Paterson. 2007. Leveraging rice genome sequence for comparative genomics in monocots. TAG 115: 237-243.
  • Yang, T.J., S.-J. Kwon, J. Kim, K.-B. Lim, J.-A. Kim, M. Jin, J.Y. Park, M.-H. Lim, H.-I. Kim, Y.P. Lim, A.H. Paterson and B.-S. Park. 2007. Characterization and Genome-wide Comparative Analysis of Terminal-Repeat Retrotransposon in Miniature (TRIM) Families in The Brassicaceae. TAG 114: 627-636.
  • Mei, H., F. Feng, B. Lu, F.A. Feltus, A.H. Paterson, X. Cai, L. Chen, X. Xu, J. Wu, X. Yu, H. Chen, Y. Li and L. Luo. 2007. Experimental validation of inter-subspecific genetic diversity in rice represented by the differences between the DNA sequences of ‘Nipponbare’ and ‘93-11.’ Chinese Science Bulletin 52: 1327-1337.
  • Yu, Q., S. Hou, R. Hobza, F.A. Feltus, X. Wang, W. Jing, R.L. Skelton, A. Blas, C. Lemke, J.H. Saw, P.H. Moore, M. Alam, J. Jiang, A.H. Paterson and R. Ming. 2007. Chromosomal location and gene paucity of the male-specific region on the papaya Y chromosome. Mol. Gen. Genet. 278: 177-185.
  • Rong, J., F.A. Feltus, V.N. Waghmare, G.J. Pierce, P.W. Chee, X. Draye, Y. Saranga, R.J. Wright, T.A. Wilkins, O.L. May, C.W. Smith, J.R. Gannaway, J.F. Wendel and A.H. Paterson. Meta-analysis of polyploid cotton QTLs shows unequal contributions of subgenomes to a complex network of genes and gene clusters implicated in lint fiber development. Genetics 176: 2577-2588.
  • Wei, F., E. Coe, W. Nelson, A. Bharti, F. Engler, E. Butler, H.-R. Kim, J.L. Goicoechea, M. Chen, S. Lee, G. Fuks, H. Sanchez-Villeda, S. Schroeder, Z. Fang, M. McMullen, G. Davis, J. Bowers, A. Paterson, M. Schaeffer, J. Gardiner, K. Cone, J. Messing, C. Soderlund and R. Wing. 2007. Physical and Genetic Structure of the Maize Genome Reflects its Complex Evolutionary History. PLoS Genetics 3: 1254-1263.
  • Desai, A., P.W. Chee, J. Rong, O.L. May and A.H. Paterson. 2006. Chromosome structural changes in diploid and tetraploid A genomes of Gossypium. Genome 49: 336-345.
  • Paterson, A.H. 2006. Leafing through the genomes of our major crop plants: strategies for capturing unique infomation. Nature Reviews Genetics 7: 174-184.
  • Udall, J.A., J. Swanson, K. Haller, R.A. Rapp, M. Sparks, J. Hatfield, Y. Yu, Y. Wu, D.J. Llewellyn, E. Dennis, A.B. Arpat, B. Sickler, T. A. Wilkins, J. Guo, X. Chen, E. Taliercio, R. Turley, C. Dowd, H. Mcfadden, N. Klueva, P. Payton, R. Allen, D. Zhang, C. Haigler, C. Wilkerson, J. Suo, S. R. Schulze, M. Pierce, M. Essenberg, H. Kim, D. Kudrna, R. Wing, A.H. Paterson, C. Soderlund and J.F. Wendel. 2006. A global assembly of cotton ESTs. Genome Research 16: 441-450.
  • Bethel, C.M., E.B. Sciara, J.E. Bowers, J.C. Estill, W. Hanna and A.H. Paterson. 2006. A framework linkage map of Bermudagrass (Cynodon dactylon x transvaalensis) based on single-dose restriction fragments. Theor. Appl. Genet. 112: 727-737.
  • Chapman, B.A., J.E. Bowers, F.A. Feltus and A.H. Paterson. 2006. Buffering crucial functions by paleologous duplicated genes may impart cyclicality to angiosperm genome duplication. Proceedings of the National Academy of Sciences of the USA 103: 2730-2735.
  • Feltus, F.A., G.E. Hart, K.F. Schertz, A.M. Casa, P. Brown, P. Klein, S. Kresovich and A.H. Paterson. 2006. Genetic Map Alignment and QTL Correspondence Between Inter- and Intra-specific Sorghum Populations. Theor. Appl. Genet. 112: 1295-1305.
  • Hamblin, M.T., A.M. Casa, H. Sun, S.C. Murray, A.H. Paterson, C.F. Aquadro and S. Kresovich. 2006. Challenges of detecting directional selection after a domestication bottleneck: lessons from Sorghum bicolor. Genetics 173: 953-954.
  • Feltus, F.A., H.P. Singh, H.C. Lohithaswa, S.R. Schulze, T. Silva and A.H. Paterson. 2006. A comparative genomics strategy for targeted discovery of single-nucleotide polymorphisms and conserved noncoding sequences in orphan crops. Plant Physiology 140: 1183-1191.
  • Gingle, A.R., H. Yang, P. Chee, O.L. May, J. Rong, D.T. Bowman, E.L. Lubbers and A.H. Paterson. An Integrated Web Resource for Cotton. Crop Science 46: 1998-2007.
  • Paterson, A.H. 2006. A cornucopia of genomes. Genome Biol. 7: 311. (meeting report)
  • Takamiya, T., A.H. Paterson and H. Okuizumi. 2006. Restriction landmark genomic scanning with isoschizomers (MspI/HpaII) for DNA methylation analysis. Electrophoresis 27: 2846-2856.
  • Jang, C.S., T.L. Kamps, D.N. Skinner, S.R. Schulze, W.K. Vencill and A.H. Paterson. 2006. Functional classification, genomic organization, putative cis-acting regulatory elements, and relationship to quantitative trait loci, of Sorghum genes with rhizome-enriched expression. Plant Physiology 142: 1148-1159.
  • Hamblin, M.T., M.G. Salas-Fernandez, A.M. Casa, S.E. Mitchell, C.F. Aquadro, A.H. Paterson and S. Kresovich. 2005. Equilibrium processes cannot explain high levels of short- and medium-range linkage disequilibrium in the domesticated grass Sorghum bicolor. Genetics 171: 1247-1256.
  • Van Becelaere, G., E.L. Lubbers, A.H. Paterson and P.W. Chee. 2005. Pedigree versus DNA marker-based genetic similarity estimates in cotton. Crop Science 45: 2281-2287.
  • Bowers, J.E., (33 authors, A.H. Paterson as corresponding author). 2005. Comparative physical mapping links conservation of microsynteny to chromosome structure and recombination in grasses. Proc. Natl. Acad. Sci. USA 102: 13206-13211.
  • Yuksel, B., J.C. Estill, S.R. Schulze and A.H. Paterson. 2005. Organization and evolution of resistance gene analogs in peanut. Molecular Genetics and Genomics 274: 248-263.
  • Rong, J.K., G.J. Pierce, V.N. Waghmare, C.A.J. Rogers, A. Desai, P.W. Chee, O.L. May, J.R. Gannaway, J.F. Wendel, T.A. Wilkins and A.H. Paterson. 2005. TAG 111: 1137-1146.
  • Rong J., J.E. Bowers, S.R. Schulze, V.N. Waghmare, C.J. Rogers, G.J. Pierce, H. Zhang, J.C. Estill and A.H. Paterson. 2005. Comparative genomics of Gossypium and Arabidopsis: Unraveling the consequences of both ancient and recent polyploidy. Genome Research 15: 1198-1210.
  • Paterson, A.H., J.E. Bowers and B.A.Chapman. 2004. Ancient polyploidization predating divergence of the cereals, and its consequences for comparative genomics. Proc. Natl. Acad. Sci. USA 101: 9903-9908.
  • Hamblin, M.T., S.E. Mitchell, G.M. White, W. Gallego, R. Kukatla, R.A. Wing, A.H. Paterson and S. Kresovich. 2004. Comparative population genetics of the panicoid grasses: Sequence polymorphism, linkage disequilibrium and selection in a diverse sample of Sorghum bicolor. Genetics 167: 471-483.
  • Rong, J.K., C. Abbey, J.E. Bowers, C.L. Brubaker, C. Chang, P.W. Chee, T.A. Delmonte, X.L. Ding, J.J. Garza, B.S. Marler, C.H. Park, G.J. Pierce, K.M. Rainey, V.K. Rastogi, S.R. Schulze, N.L. Trolinder, J.F. Wendel, T.A. Wilkins, T.D. Williams-Coplin, R.A. Wing, R.J. Wright, X.P. Zhao, L.H. Zhu and A.H. Paterson. 2004. A 3347-locus genetic recombination map of sequence-tagged sites reveals features of genome organization, transmission and evolution of cotton (Gossypium). Genetics 166: 389-417.
  • Ma, H., P.H. Moore, Z.Y. Liu, M.S. Kim, Q.Y. Yu, M.M.M. Fitch, T. Sekioka, A.H. Paterson and R. Ming. 2004. High-density linkage mapping revealed suppression of recombination at the sex determination locus in papaya. Genetics 166: 419-436.
  • Saranga, Y., C.X Jiang., R.J. Wright, D. Yakir and A.H. Paterson. 2004. Genetic dissection of cotton physiological responses to arid conditions and their inter-relationships with productivity. Plant Cell and Environment 27: 263-277.
  • Liu, Z.Y., P.H. Moore, H. Ma, C.M. Ackerman, M. Ragiba, Q.Y. Yu, H.M. Pearl, M.S. Kim, J.W. Charlton, J.I. Stiles, F.T. Zee, A.H. Paterson, and R. Ming. 2004. A primitive Y chromosome in papaya marks incipient sex chromosome evolution. Nature 427: 348-352.
  • Bowers, J.E., C. Abbey, S. Anderson, C. Chang, X. Draye, A.H. Hoppe, R. Jessup, C. Lemke, J. Lennington, Z.K. Li, Y.R. Lin, S.C. Liu, L.J. Luo, B.S. Marler, R.G. Ming, S.E. Mitchell, D. Qiang, K. Reischmann, S.R. Schulze, D.N. Skinner, Y.W. Wang, S. Kresovich, K.F. Schertz and A.H. Paterson. 2003. A high-density genetic recombination map of sequence-tagged sites for Sorghum, as a framework for comparative structural and evolutionary genomics of tropical grains and grasses. Genetics 165: 367-386.
  • Hu, F.Y., D.Y. Tao, E. Sacks, B.Y. Fu, P. Xu, J. Li, Y. Yang, K. McNally, G.S. Khush, A.H. Paterson and Z.K. Li. 2003. Convergent evolution of perenniality in rice and sorghum. Proc. Natl. Acad. Sci. USA 100: 4050-4054.
  • Bowers, J.E., B.A. Chapman, J.K. Rong and A.H. Paterson. 2003. Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events. Nature 422: 433-438.
  • Paterson, A.H., J.E. Bowers, M.D. Burow, X. Draye, C.G. Elsik, C.X. Jiang, C.S. Katsar , T.H. Lan, Y.R. Lin, R.G. Ming and R.J. Wright. 2000. Comparative genomics of plant chromosomes. Plant Cell 12: 1523-1539.
  • Jiang, C.X., P.W. Chee, X. Draye, P.L. Morrell, C.W. Smith and A.H. Paterson. 2000. Multilocus interactions restrict gene introgression in interspecific populations of polyploid Gossypium (cotton). Evolution 54: 798-814.
  • Wright, R.J., P.M. Thaxton, K.M. El-Zik and A.H. Paterson. 1998. D-subgenome bias of Xcm resistance genes in tetraploid Gossypium (Cotton) suggests that polyploid formation has created novel avenues for evolution. Genetics 149: 1987-1996.
  • Jiang, C.X., R.J. Wright, K.M. El-Zik and A.H. Paterson. 1998. Polyploid formation created unique avenues for response to selection in Gossypium (cotton). Proc. Natl. Acad. Sci. USA 95: 4419-4424.
  • Multani, D.S., R.B. Meeley, A.H. Paterson, J. Gray, S.P. Briggs and G.S. Johal. 1998. Plant-pathogen microevolution: Molecular basis for the origin of a fungal disease in maize. Proc. Natl. Acad. Sci. USA 95: 1686-1691.
  • Paterson, A.H., T.H. Lan, K.P. Reischmann, C. Chang, Y.R. Lin, S.C. Liu, M.D. Burow, S.P. Kowalski, C.S. Katsar, T.A. DelMonte, K.A. Feldmann, K.F. Schertz and J.F. Wendel. 1997. Toward a unified genetic map of higher plants, transcending the monocot-dicot divergence. Nature Genetics 14: 380-382.
  • Paterson, A.H., Y.R. Lin, Z.K. Li, K.F. Schertz, J.F. Doebley, S.R.M. Pinson, S.C. Liu, J.W. Stansel, and J.E. Irvine. 1995. Science 269: 1714-1718.
  • Paterson, A.H., E.S. Lander, J.D. Hewitt, S. Peterson, S.E. Lincoln and S.D. Tanksley. 1988. Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms. Nature 335: 721-726.
  • “Grass Genome Biodiversity,” NSF
  • “Comparative Evolutionary Genomics of Cotton,” NSF
  • “The Science Behind our Food,” NSF
  • “Sequencing the Genome of Azospirillum,” NSF/USDA/DOE
  • “Sex Determination in Papaya,” NSF