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Jessica Kissinger
Associate Professor
Director, Institute of Bioinformatics
Ph.D. (1995) Indiana University
Phone: 706-542-6562
Email: jkissing@uga.edu
See Institute of Bioinformatics
See my Laboratory Home Page
Research Interests
How do eukaryotic genomes evolve? Our lab is interested in parasite genomics and the biology of genome evolution. The genomes of parasitic eukaryotes are often highly reduced, devoid of recognizable mobile elements and riddled with intracellular and lateral gene transfers. Our approach is to apply molecular, computational and phylogenetic tools to the analysis of dozens of complete parasite genomes. Projects include the development of tools for data mining, comparative genomics and assessment of the phylogenetic distribution of genes. We welcome students interested in working on the bench, at the computer, or both.
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- Li, Z.-H., J.G. De Gaudenzi, V.E. Alvarez, H. Wang, J. Kissinger, A.C. Frasch, and R. Docampo. An 43-nt AU-rich Element in the 3'UTR Region of a Large Number of Trypanosoma cruzimRNAs is Important for mRNA Stability in Intracellular Amastigotes. (Submitted)
- Lucchi, N.W., M. Poorak, J. Oberstaller, J. DeBarry., G. Srinivasamoorthy, I.Goldman, M. Xayavong, A. DaSilva, D.S. Peterson, J. Barnwell, J.C. Kissinger, and V. Udhayakumar. A new single-step PCR target for the detection of P. knowlesi. PLoS ONE. 2012 7(2): e31848. doi:10.1371/journal.pone.0031848
- Wang, Y., H. Tang, J.D. DeBarry, X. Tan, J. Li, X. Wang, T. Lee, H. Jin, B. Marler, H. Guo, J.C. Kissinger, and A.H. Paterson. MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Res. 2012 Jan 4
- Stajich, J., T. Harris, B. Brunk, J. Brestelli, S. Fischer, O. Harb, J.C. Kissinger, W. Li, V. Nayak, D. Pinney, C. Stoeckert, and D. Roos. FungiDB: an integrated functional genomics database for fungi. Nucleic Acids Res. 2012 Jan;40(Database issue):D675-81.
- Satomi, K. and J.C. Kissinger. 2012 Cryptosporidium: Comparative Genomics and Pathogenesis. In Evolution of Virulence in Eukaryotic Microbes. David Sibley, Barbara J. Howlett, and Joseph Heitman (eds.). Wiley-Blackwell. (In Press)
- DeBarry, J., S. Fatumo, and J.C. Kissinger. 2012. The genomic landscape - How doesPlasmodium compare to other apicomplexan species? In Comparative Genomics of Plasmodium Parasites. Carlton, Perkins, and Deitsch (eds.). Horizon Scientific Press, Norwich, UK. (In Press)
- Phillips, J.E., M.W. Jackwood, E.T. McKinley, S.W. Thor, D.A. Hilt, N.D. Acevedo1, S.M. Williams, J.C. Kissinger, A.H. Paterson, J.S. Robertson, and C. Lemke. Changes in Nonstructural Protein 3 are Associated with Attenuation in Avian Coronavirus. Virus Genes, Epub Sept 10.
- Thor, S., D. Hilt, J.C. Kissinger, A. Paterson, and M. Jackwood. 2011. Recombination in avian gamma-coronaviruses. Viruses 3: 1777-1799 doi:10.3390/v3091777
- Guttula, C., A. Dhamanaskar, R. Wang, J.A. Miller, J.C. Kissinger, J. Zheng, and C.J. Stoeckert, Jr. 2011. Enriching the Ontology for Biomedical Investigations (OBI) to Improve its Suitability for Web Service Annotations. International Conference on Biomedical Ontology (ICBO). In Proceedings of the 2011 International Conference on Biomedical Ontology (ICBO), Buffalo, New York, pp. 246-258.
- Wang, R., C. Guttula, M. Panahiazar, H. Yousaf, J.A. Miller, E.T. Kraemer, and J.C. Kissinger. 2011. Web Service Composition using Service Suggestions. In Proceedings of the 2011 IEEE International Workshop on Formal Methods in Services and Cloud Computing (FM-S&C) in conjunction with the 2011 IEEE. International Conference on Web Services (ICWS), pp. 482-489.
- Kissinger, J.C. and J. DeBarry. 2011. Genome cartography: charting the apicomplexan genome. Trends in Parasitology 27: 345-354.
- Fischer, S., C. Aurrecoechea, B.P. Brunk, X. Gao, O.S. Harb, E.T. Kraemer, C. Pennington, C.Treatman, J.C. Kissinger, D.S. Roos, and C.J. Stoeckert. 2011. The Strategies WDK: a graphical search interface and web development kit for functional genomics databases. DATABASE - The Journal of Biological Databases and Curation doi:10.1093/database/bar027.
- McKinley, E.T., M.W. Jackwood, D.A. Hilt, J.C. Kissinger, A.H. Paterson, J.S. Robertson, and C. Lemke. 2011. Attenuated live vaccine usage affects accurate measures of virus diversity and evolutionary rates in avian coronavirus infectious bronchitis virus. Virus Research 158: 225–234.
- Demas, A. J. Oberstaller, J. DeBarry, N.W. Lucchi, G. Srinivasamoorthy, D. Sumari, A.M. Kabanywanyi, L. Villegas, A. A. Escalante, S.P. Kachur, J.W. Barnwell, D.S. Peterson, V. Udhayakumar, and J.C. Kissinger. 2011. Applied genomics: Data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA. J. Clinical Microbiology doi:10.1128/JCM.02603-10.
- DeBarry, J. and J.C. Kissinger. 2011. Jumbled Genomes: Missing Apicomplexan Synteny1. Molecular Biology and Evolution doi:10.1093/molbev/msr103.
- Aurrecoechea, C., A. Barreto, J. Brestelli, B.P. Brunk, E. V. Caler, S. Fischer, B. Gajria, X. Gao, A. Gingle, G. Grant, O.S. Harb, M. Heiges, F. J. Iodice, J.C. Kissinger, E.T. Kraemer, W. Li, V. Nayak, C. Pennington, D.F. Pinney, D.S. Roos, C. Ross, G. Srinivasamoorthy, C.J. Stoeckert Jr., C. Treatman, and H. Wang. 2010. AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species. Nucleic Acids Research doi:10.1093/nar/gkq1006.
- Joseph, S.J., J. A. Fernandez-Robledo, M. J. Gardner, N.M. El-Sayed, C-H. Kuo, E. J. Schott, H. Wang, J. C. Kissinger, and G. R. Vasta. 2010. The Alveolate Perkinsus marinus: Biological Insights from EST Gene Discovery. BMC Genomics 11: 228.
- Jackwood, M.W., T.O. Boynton, D.A. Hilt, E.T. McKinley, J.C. Kissinger, A.H. Paterson, J. Robertson, C. Lemke, A.W. McCall, S.M. Williams, J.W. Jackwood, and L. Byrd. 2010. Emergence of a group 3 coronavirus through recombination. Virology 398: 98-108.
- H. Wang, J. DeBarry, and J. C. Kissinger. 2010. SynView - Synteny Browser with GBrowse Integration 2010. In A Practical Guide to Bioinformatics Analysis. Gabriel P.C. Fung (ed.). iConcept Press.
- Aurrecoechea, C., J. Brestelli, B.P. Brunk, S. Fischer, B. Gajria, J. Gao, A. Gingle, G. Grant, O.S. Harb, M. Heiges, F. Innamorato, J. Iodice, J.C. Kissinger, E.T. Kraemer, W. Li, J.A. Miller, V. Nayak, C. Pennington, D.F. Pinney, D.S. Roos, C. Ross, G. Srinivasamoorthy, C.J. Stoeckert Jr., R. Thibodeau, C. Treatman, and H. Wang. 2010. EuPathDB: a Portal to Eukaryotic Pathogen Databases. Nucleic Acids Research 38: D415-419.
- Aslett, M., C. Aurrecoechea, M. Berriman, J. Brestelli, B. P. Brunk, M. Carrington, D. P. Depledge, S. Fischer, B. Gajria, X. Gao, M. J. Gardner, A. Gingle, G. Grant, O. S. Harb, M. Heiges, C. Hertz-Fowler, R. Houston, F. Innamorato, J. Iodice, J. C. Kissinger, E. Kraemer, W. Li, F. Logan, J. A. Miller, S. Mitra, P. J. Myler, V. Nayak, C. Pennington, I. Phan, D. F. Pinney, G. Ramasamy, M. Rogers, D. S. Roos, C. Ross, D. Sivam, D. F. Smith, G. Srinivasamoorthy, C. J. Stoeckert Jr., S. Subramanian, R. Thibodeau, A. Tivey, C. Treatman, G. Velarde, and H. Wang. 2010. TriTrypDB: A Functional Genomic Resource for the Trypanosomatidae. Nucleic Acids Research 38: D457-462.
- Wang, Z. X. Gao, C. He, J.A. Miller, J.C. Kissinger, M. Heiges, C. Aurrecoechea, E.T. Kraemer, and C. Pennington 2009. An Evaluation of Multiple Approaches for Federating Biological Data. Journal of Information Technology Research 2: 42-64.
- Balu, B., C. Chauhan, S.P. Maher, D.A. Shoue, J.C. Kissinger, M.J. Fraser Jr., and J.H. Adams. 2009. piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome. BMC Microbiology 9: 83.
- Putignani, L., Sanya J. Sanderson, C. Russo, J. Kissinger, D. Menichella, and J.M. Wastling. 2009. Proteomic and genomic approaches to understanding the "power plant" of Cryptosporidium. In Giardia and Cryptosporidium: from molecules to disease. Ortega-Pierres,G., Caccio, S., Faryer, R., Mank, T.G., Smith, H., Thompson, R.C.A. (eds.). CABI publishing.
- Storm, K., E. Kraemer, C. Aurrecoechea, M. Heiges, C. Pennington, and J.C. Kissinger. 2009. Web Site Evolution: Usability Evaluation Using Time Series Analysis of Selected Episode Graphs. 11th IEEE International Symposium on Web Systems Evolution (WSE'09).
- Wang, R., D. Brewer, S. Shastri, S. Swayampakula, J.A. Miller, E.T. Kraemer, and J.C. Kissinger. 2009. Adapting the Galaxy Bioinformatics Tool to Support Semantic Web Service Composition. In Proceedings of the 3-rd IEEE International Workshop on Scientific Workflows (SWF'09), in conjunction with the 2009 IEEE International Conference on Web Services (ICWS'09), Los Angeles, California. July 2009: 283-290.
- Mullapudi, N. and J.C. Kissinger. 2009. Identification and functional characterization of cis-regulatory elements in the apicomplexan parasite Toxoplasma gondii. Genome Biology 10: R34.
- Aurrecoechea C., J. Brestelli, B. Brunk, J. Dommer, S. Fischer, B. Gajria, X. Gao, A. Gingle, G. Grant, O. Harb, M. Heiges, F. Innamarato, J. Iodice, J.C. Kissinger, E. Kraemer, W. Li, J. Miller, V. Nayak, D. Roos, and C. Stoeckert. 2009. PlasmoDB: A functional genomic database for malaria parasites. Nucleic Acids Research 37: D539-43.
- Aurrecoechea, C., J. Brestelli, B.P. Brunk, J.M. Carlton, J. Dommer, S. Fischer, B. Gajria, J. Gao, A. Gingle, G. Grant, O.S. Harb, M. Heiges, F. Innamorato, J. Iodice, J.C. Kissinger, E. Kraemer, W. Li, J.A. Miller, H.G. Morrison, V. Nayak, C. Pennington, D.F. Pinney, D.S. Roos, C. Ross, C.J. Stoeckert Jr., S. Sullivan, C. Treatman, and H. Wang. 2009. GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Research 37: D526-30.
- Zerlotini A., Heiges M., Wang H., Moraes R., Dominitini A., Ruiz J., Kissinger J., and G. Oliveira. 2009. SchistoDB: a Schistosoma mansoni genome resource. Nucleic Acids Research 37 :D579-82.
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